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HESS-5 cells restore HES-1 protein expression in primary CLL cells. Western blot analysis of HES-1 protein expression in primary CLL cells treated with CTX (0.5 or 1.0 µM) for 24 h, followed by additional 48 h of co-culture with a HESS-5 cell monolayer. A representative image of three independent experiments is shown. HES-1, Hes family BHLH transcription factor 1; CTX, cyclophosphamide; CLL, chronic lymphocytic leukemia.
