Table 1. Structures and experimental activity6,7,10 of inhibitors targeting menin–MLL interaction.

Inhibitor	Structure	IC50 [μM]
MI-2-2 a		0.046
MI-859 b		0.065
MI-319 b		0.082
MI-2-3 b		0.092
MI-836 b		0.260
MI-2 c		0.45
MI-273 b		0.674
MI-20 c		0.75
MI-2-4 a		0.765
MI-326 b		0.779
MI-19 b		1.200
MI-333 b		1.653
MI-12 c		14
MI-16 c		46
MI-4 c		52
MI-10 c		58
MI-11 c		87
MI-6 c		193

^aInhibitory activity values are taken from ref. 7.

^bInhibitory activity values are taken from ref. 10.

^cInhibitory activity values are taken from ref. 6.