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. 2017 Nov 22;15(2):1330–1338. doi: 10.3892/etm.2017.5539

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Copyright: © An et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 7. — Brain edema and neurological deficit evaluation following administration of AG490 at day 1 after SAH. (A) Brain water content was significantly higher in the SAH and SAH + DMSO groups compared with the Sham group at day 1 after SAH. AG490 administration significantly reduced brain edema after SAH compared with the SAH and SAH + DMSO groups; (B) Neurological scoring was significantly lower in the SAH and SAH + DMSO groups compared with the Sham group at days 1, 3 and 7 after SAH. However, neurological deficits significantly improved in the SAH + AG490 group compared with the SAH and SAH + DMSO groups at days 1, 3 and 7 after SAH. Data are presented as the mean ± standard deviation. *P<0.05 vs. the SAH and SAH + DMSO groups. SAH, subarachnoid hemorrhage; DMSO, dimethyl sulfoxide.