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. 2017 Nov 28;15(2):1753–1757. doi: 10.3892/ol.2017.7497

Table II.

Independent risk factors for the prognosis of LUSC patients.

Univariate analysis Multivariate analysis


Factor HR (95% CI) P-value HR (95% CI) P-value
miR-590 1.647 0.009 2.152 0.004
(low vs. high) (1.122–2.896) (1.285–3.233)
Age 1.014 0.062
(>60 vs. ≤60) (0.999–1.029)
Sex 0.819 0.788
(male vs. female) (0.277–2.424)
Pathological staging 2.143 0.013 1.268 0.113
(low vs. high/medium differentiation) (1.288–2.715) (0.918–2.471)
Maximum diameter of tumor 0.812 0.682
(>50 mm vs. ≤50 mm) (0.357–1.847)
Lymph node metastasis 3.064 0.012 1.097 0.013
(positive vs. negative) (1.282–7.323) (0.336–3.582)
Distant metastasis 2.124 0.001 1.984 0.005
(positive vs. negative) (1.557–4.575) (1.137–3.754)
TNM staging 2.112
(III/IV vs. I/II) (1.231–3.625) 0.036

LUSC, lung squamous cell carcinoma; HR, hazard ratio; CI, confidence interval; miR-590, micro ribonucleic acid-590; TNM, tumor, node and metastasis.