Table II.
Univariate analysis | Multivariate analysis | |||
---|---|---|---|---|
Factor | HR (95% CI) | P-value | HR (95% CI) | P-value |
miR-590 | 1.647 | 0.009 | 2.152 | 0.004 |
(low vs. high) | (1.122–2.896) | (1.285–3.233) | ||
Age | 1.014 | 0.062 | ||
(>60 vs. ≤60) | (0.999–1.029) | |||
Sex | 0.819 | 0.788 | ||
(male vs. female) | (0.277–2.424) | |||
Pathological staging | 2.143 | 0.013 | 1.268 | 0.113 |
(low vs. high/medium differentiation) | (1.288–2.715) | (0.918–2.471) | ||
Maximum diameter of tumor | 0.812 | 0.682 | ||
(>50 mm vs. ≤50 mm) | (0.357–1.847) | |||
Lymph node metastasis | 3.064 | 0.012 | 1.097 | 0.013 |
(positive vs. negative) | (1.282–7.323) | (0.336–3.582) | ||
Distant metastasis | 2.124 | 0.001 | 1.984 | 0.005 |
(positive vs. negative) | (1.557–4.575) | (1.137–3.754) | ||
TNM staging | 2.112 | |||
(III/IV vs. I/II) | (1.231–3.625) | 0.036 |
LUSC, lung squamous cell carcinoma; HR, hazard ratio; CI, confidence interval; miR-590, micro ribonucleic acid-590; TNM, tumor, node and metastasis.