Figure 5.

Knockdown of BDNF has a similar effect to that of microRNA-613 overexpression in gastric cancer cells. (A) BDNF protein expression was determined in SGC-7901 cells transfected with si-BDNF or si-NC. β-actin was used for as an internal control. (B) Proliferation, (C) migration and (D) invasion of MG63 cells were determined after transfection with si-BDNF or si-NC. *P<0.05, **P<0.01. si-BDNF, small interfering RNA targeting brain-derived neurotrophic factor; si-NC, scrambled control small interfering RNA.