Table I.

Top 10 most upregulated and downregulated DEGs in patients with ankylosing spondylitis.

A, Upregulated DEGs
Gene	log2 fold change	t-value	P-value
SIGLEC1	3.25845	4.26359	5.0×10−5
VSIG4	4.02414	4.19381	5.0×10−5
BATF2	2.55908	3.45345	5.0×10−5
IFIT1	2.09875	3.29697	5.0×10−5
IFIT3	2.14216	3.1677	5.0×10−5
SERPING1	2.00997	3.03775	5.0×10−5
RSAD2	2.45907	2.96724	5.0×10−5
CASP5	3.04181	2.93592	5.0×10−5
MCEMP1	2.20974	2.92794	5.0×10−5
LOC441081	2.63115	2.79881	5.0×10−5
B, Downregulated DEGs
Gene	log2 fold change	t-value	P-value
GPR162	−2.24236	2.24236	5.0×10−5
HAPLN3	−2.47863	−2.47863	5.0×10−5
PTGDS	−2.64354	−2.64354	5.0×10−5
FCGBP	−2.32069	−2.32069	2.5×10−4
GZMM	−2.06931	−2.06931	5.5×10−4
SH2D1B	−1.91722	−1.91722	6.0×10−4
TIGD3	−2.05767	−2.05767	6.0×10−4
LGALS9C	−1.91957	−1.91957	6.5×10−4
KIR2DL3	−2.24251	−2.24251	9.5×10−4
COL6A2	−1.87265	−1.8726	1.4×10−3