Table II.

Top six transcription factors regulating the majority of differentially expressed genes identified in patients with ankylosing spondylitis.

TF	No. of DEGs regulated	DEG
1-Oct	13	SH2D1B, RSAD2, LOC441081, VSIG4, IFIT1, IFIT3, SERPING1, CASP5, BATF2, GPR162, LGALS9C, KIR2DL3, MCEMP1
Pax-4	13	SH2D1B, LOC441081, IFIT3, IFIT1, SERPING1, BATF2, TIGD3, HAPLN3, LGALS9C, GZMM, MCEMP1, COL6A2, KIR2DL3
HNF-4	7	SH2D1B, RSAD2, LOC441081, VSIG4, IFIT3, BATF2, COL6A2
Nkx2-5	7	IFIT3, IFIT1, SERPING1, BATF2, LGALS9C, GZMM, KIR2DL3
Evi-1	6	SH2D1B, SERPING1, CASP5, BATF2, LGALS9C, KIR2DL3
HNF-1	6	RSAD2, LOC441081, IFIT1, CASP5, GPR162, KIR2DL3

DEG, differentially expressed gene; TF, transcription factor.