Table III.
Clinical characteristics of the Crohn's disease patients.
| Case | Year of birth | Sex | Year of onset | Year of diagnosis | Location of lesion | Disease phenotype | Treatment | EIM | Surgery | CDAI |
|---|---|---|---|---|---|---|---|---|---|---|
| F1-II6 | 1968 | M | 2000 | 2002 | Terminal ileum + rectum | Stricturing | Mesalazine + corticosteroids | No | No | 4 |
| F1-III6 | 1996 | F | 2012 | 2012 | Terminal ileum + ileocecus + ascending colon + rectum + upper gastrointestinal tract | Penetrating | Mesalazine + corticosteroids + biological agents + azathioprine | Yes | No | 11 |
| F2-III5 | 1981 | M | 2004 | 2006 | Terminal ileum + ileocecus + rectum | Stricturing | Mesalazine + corticosteroids + azathioprine | No | Yes | 9 |
| F2-III6 | 1981 | M | 2009 | 2009 | Terminal ileum + ileocecus | Stricturing | Mesalazine + corticosteroids + biological agents + azathioprine | No | Yes | 11 |
| F3-III2 | 1973 | M | 2013 | 2013 | Terminal ileum + ileocecus | Non-penetrating + non-stricturing | Mesalazine | No | No | 1 |
| F3-III4 | 1975 | M | 2009 | 2010 | Terminal ileum + ileocecus + rectum | Penetrating | Mesalazine + corticosteroids + azathioprine | No | Yes | 11 |
| F3-III8 | 1987 | F | 2012 | 2012 | Terminal ileum + ileocecus + rectum | Non-penetrating + non-stricturing | Mesalazine | No | No | 6 |
| F3-III10 | 1979 | F | 2013 | 2013 | Terminal ileum + ileocecus | Non-penetrating + non-stricturing | Mesalazine | No | No | 1 |
F1, family 1; F2, family 2; F3, family 3; M, male; F, female; EIM, extraintestinal manifestations; CDAI, Crohn's disease activity index.