Table 2.

Odds Ratios for Mortality and Composite Outcomes by Risk Factor.^a,b

Patients With Suspected Infection (N = 5992)	Unadjusted Odds Ratio	Adjusted Odds Ratio (95% Confidence Interval)
Model 1: Mortality outcome
Age	1.02	1.03 (1.02-1.04)
Male sex	1.69	1.73 (1.31-2.28)
Readmission (<30 days)	1.88	1.81 (1.26-2.59)
qSOFA	2.82	2.49 (1.79-3.45)
Model 2: Mortality outcome
Age	1.02	1.03 (1.02-1.04)
Male sex	1.69	1.65 (1.25-2.18)
Readmission (<30 days)	1.88	1.99 (1.38-2.86)
SJSA “Sepsis alert”	3.40	4.65 (3.35-6.46)
SJSA “SIRS alert”	1.36	2.36 (1.67-3.35)
Model 3: Composite outcome
Age	1.01	1.01 (1.00-1.01)
Male sex	1.26	1.27 (1.11-1.46)
Readmission (<30 days)	1.31	1.24 (1.01-1.53)
qSOFA	1.58	2.10 (1.70-2.58)
Model 4: Composite outcome
Age	1.01	1.01 (1.00-1.01)
Male sex	1.26	1.21 (1.05-1.39)
Readmission (<30 days)	1.31	1.32 (1.07-1.63)
SJSA “Sepsis alert”	2.64	3.49 (2.93-4.16)
SJSA “SIRS alert”	1.40	2.19 (1.85-2.59)

Abbreviations: CI, confidence interval; qSOFA, Quick Sequential [Sepsis-related] Organ Failure Assessment; SIRS, systemic inflammatory response syndrome; SJSA, St. John Sepsis Surveillance Agent.

^aModel performance:

Model 1: C-statistic = 0.69, 95% CI (0.66 to 0.73).

Model 2: C-statistic = 0.74, 95% CI (0.71 to 0.77).

Model 3: C-statistic = 0.65, 95% CI (0.64 to 0.67).

Model 4: C-statistic = 0.72, 95% CI (0.71 to 0.74).

^bAge in one-year increments. Readmission (<30 days) indicates patient was discharged within previous 30 days and now admitted to the same hospital.