Table 1B.
Ligand | Nanosystem | Key results | Ref. |
---|---|---|---|
IgG coating | SPIO | Higher in vitro uptake and sustained distribution in lymphoid tissue, in comparison to non-coated SPIO | [85] |
Mannosylation | Liposomes | Functionalized liposomes accumulated in tumor-associated macrophages better than in other lung areas | [86] |
Folate | Dendrimer (G5) | High in vitro internalization by macrophages in a receptor-specific manner and great in vivo anti-inflammatory properties | [88] |
Dextran | Dextran conjugates | After peritoneal administration, larger conjugates selectively associated with macrophages of the adipose tissue | [89] |
G5: generation 5; IgG: immunoglobulin G; SPIO: superparamagnetic iron-oxide nanoparticles