Table 3.
Association of rs9608282 in ADORA2A with neuroimaging phenotypes and memory composite scores with and without diagnosis (DX) adjustment. SNP-based association results (p-values) in the discovery sample for hippocampal volume, neurogenesis-related hippocampal sub-regions, memory performance, and CSF total tau level.
| rs9608282 |
p-value after adjusting for DX |
p-value without adjusting for DX |
|---|---|---|
| Hippocampal Volume | 3.29×10−4 | 1.14×10−5 |
| Neurogenesis-Related Hippocampal Sub-regions | 4.55×10−3 | 2.50×10−4 |
| Memory Composite Score | 2.18×10−1 | 7.45×10−3 |
| CSF Total Tau | 2×10−1 | 2.3×10−2 |