. Author manuscript; available in PMC: 2018 Jan 19.

Published in final edited form as: Toxicol Lett. 2006 Apr 18;165(2):182–194. doi: 10.1016/j.toxlet.2006.03.008

Table 2.

CSC-repressed genes

GenBank	Symbol	Gene name	Gene function	Average fold change (decrease)
GenBank	Symbol	Gene name	Gene function	NHEK	Leuk1	Leuk2	101A
BC005961	PTHLH	Parathyroid hormone-like hormone	Cell–cell signaling, cell proliferation	4.29	1.01	1.55	7.04
U41815	NUP98	Nucleoporin 98 kDa	Intracellular protein transport	3.34	1.68	1.11	3.62
NM 023007	FLJ12517	Hypothetical protein FLJ12517	Unknown	3.13	1.76	1.59	1.85
NM 024098	MGC2574	Hypothetical protein MGC2574	Regulation of transcription	2.82	1.07	1.12	2.60
NM 006795	EHD1	EH-domain containing 1	Unknown	2.15	1.01	1.60	2.39
NM 003017	SFRS3	Splicing factor, arginine/serine-rich 3	Regulation of transcription	2.03	1.21	1.58	1.86
AF109294	MTAP	Methylthioadenosine phosphorylase	Regulation of transcription	1.87	1.39	2.22	1.42
NM 003457	ZNF207	Zinc finger protein 207	Regulation of transcription	1.69	1.02	1.49	2.83

The list includes eight genes down-regulated (≥2-fold; p < 0.005) in CSC-treated (25 μg/ml, 24 h) vs. untreated cells in any one of the cell lines NHEK, Leuk1, Leuk2 and 101A. Assignments of gene functions to biological processes were extracted using PathwayAssist datamining software. Fold changes are derived from the averages of two independent microarray experiments.