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. 2018 Jan 15;13:317–324. doi: 10.2147/COPD.S149835

Table 3.

Impact of comorbidities on empyema among COPD patients (n=55,136)

Comorbidity Number (%) Event aHR (95% CI) P-value
No comorbidity 20,285 (36.8) 126
Diabetes only 1,596 (2.9) 16 1.65 (0.98–2.78) 0.06
Hypertension only 10,271 (18.6) 68 1.05 (0.78–1.42) 0.73
Chronic liver disease only 1,788 (3.2) 14 1.24 (0.72–2.16) 0.44
Stroke only 1,612 (2.9) 17 1.88 (1.13–3.11) 0.02
Cancer only 271 (0.5) 5 4.84 (1.97–11.8) 0.001
Chronic renal disease only 153 (0.3) 3 3.90 (1.24–12.3) 0.02
≥1 comorbidity 34,851 (63.2) 260 1.25 (1.01–1.55) 0.04
≥2 comorbidities 17,152 (31.1) 129 1.29 (1.01–1.65) 0.04
≥3 comorbidities 6,057 (11.0) 53 1.54 (1.11–2.12) 0.01

Abbreviation: aHR, adjusted hazard ratio.