Table 2. Results of univariate analysis for BPE.
| Investigated parameters in association with BPE | Original scores BPE by R1 | Original scores BPE by R2 | P-value R1$ | P-value R1# | P-value R2$ | P-value R2# |
|---|---|---|---|---|---|---|
| Grade | grade 1/ 2 /3 | grade 1/ 2 /3 | 0.040* | 0.016* | 0.008* | 0.003* |
| 1. Minimal BPE | 1/14/14 | 0/13/14 | ||||
| 2. Mild BPE | 2/7/12 | 4/10/17 | ||||
| 3. Moderate BPE | 5/5/8 | 5/5/3 | ||||
| 4. Marked BPE | 3/5/1 | 2/3/1 | ||||
| Missing: 0 | ||||||
| PR status | PR+/ PR- | PR+/ PR- | 0.089 | 0.018* | 0.015* | 0.021* |
| 1. Minimal BPE | 7/14 | 5/16 | ||||
| 2. Mild BPE | 7/10 | 13/11 | ||||
| 3. Moderate BPE | 11/5 | 8/3 | ||||
| 4. Marked BPE | 5/2 | 4/1 | ||||
| Missing: 17 | ||||||
| Scored motion per reader | minimal/ mild/ moderate/ and severe | minimal/ mild/ moderate/ and severe | 0.038* | 0.009* | 0.031* | 0.066 |
| 1. Minimal BPE | 17/8/3/1 | 20/7/0/0 | ||||
| 2. Mild BPE | 17/3/1/0 | 19/6/6/0 | ||||
| 3. Moderate BPE | 4/7/5/2 | 7/6/0/0 | ||||
| 4. Marked BPE | 4/3/2/0 | 4/2/0/0 | ||||
| Missing: 0 |
$ P-values are based on original data (including the 4 BPE categories) using Chi-square tests
# P-values are based on dichotomized values using Chi-square tests
* is indicating a p-value ≤ 0.05.
PR: Progesterone receptor. Insignificant factors included: age (p≥0.284 for original BPE values and p≥0.188 for dichotomized BPE values), menopause (p≥0.119and p≥0.055), invasiveness (p≥0.383and p≥0.234), cancer type (p≥0.284 and p≥0.055), T-stage (p≥0.242 and p≥0.230), N-stage (p≥0.356 and p≥0.175), molecular subtype (p≥0.165 and p≥0.061), ER-status (p≥0.119 and p≥0.055), and HER2-status (p≥0.700 and p = 0.999).