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. 2018 Jan 19;13(1):e0191342. doi: 10.1371/journal.pone.0191342

Table 2. Significant associations between the different variables evaluated and pain and effusion at one month and at one year follow-up.

Variables* Women
N (%)/mean
Men
N (%)/mean
Yes No Yes No
p value p value
Pain at one year Obesity Yes 29 (70%) 33 (47%) 7 (70%) 4 (36.4%)
No 12 (30%) 37 (53%) 3 (30%) 7 (63.6%)
0.0183 0.1984
BMI 32.7 (4.38) 30.4 (4.48) 33.3 (5.19) 30.2 (3.91)
0.009 0.1429
WC 104.2 (9.2) 99.3 (10.1) 116.3 (12.8) 107.9 (14.7)
0.0116 0.1793
% Body Fat 43.5 (3.78) 40.7 (4.87) 32.1(4.66) 30.3 (4.33)
0.002 0.3577
Lequesne 15.9 (3.14) 12.3 (3.6) 13.3 (4.11) 11.4 (3.95)
< 0.0001 0.2853
Pain at one month Yes 25 (61%) 5 (7.2%) 7 (70%) 1 (9%)
No 16 (39%) 65 (92.8%) 3 (30%) 10 (91%)
< 0.0001 0.0075
Effusion at one month Yes 24 (58.5%) 4 (5.7%) 8 (80%) 2 (18.2%)
No 17 (41.5%) 66 (94.3%) 2 (20%) 9 (81.8%)
< 0.0001 0.0089
Effusion at one yearʺ Yes 22 (70.9%) 6 (8.5%) 5 (50%) 2 (18.2%)
No 19 (29.1%) 64 (93.5%) 5 (50%) 9 (81.8%)
<0.0001 0.1224
Effusion at one year WC 104.1 (9.2) 100.1(10.2) 117.2 (11.4) 109.3 (15.1)
0.0696 0.2413
US effusion (mm) # 10.5 (2.85) 8.94 (2.6) 9.81 (2.52) 9.96 (2.96)
0.0041 0.9101
US synovial hypertrophy (mm) # 5.18 (2.2) 3.99 (1.8) 4.04 (1.65) 4.75 (2.59)
0.0057 0.518
Lequesne 15.3 (3.25) 13.1 (3.91) 14.14 (4.37) 11.35 (3.69)
0.0086 0.1413
Pain at one month Yes 15 (53.5%) 15 (18%) 6 (85.7%) 2 (14.2%)
No 13 (46.5%) 68 (82%) 1 (14.3%) 12 (85.8%)
0.0005 0.0032
Effusion at one month Yes 20 (71.4%) 8 (9.6%) 7 (100%) 3 (21.5%)
No 8 (28.6%) 75 (90.4%) 0 (0%) 11 (78.5%)
< 0.0001 0.001

BMI: Body Mass Index, CI: Confidence Interval, CRP: C-reactive protein, SD: standard deviation, US: Ultrasound, WC: Waist Circumference.

Continuous variables were expressed using means and standard deviation. Comparisons were performed by T-student test (p value reported in the lower line). Categorical variables were expressed by absolute frequencies, percentages and CI of 95%; comparisons were performed using a Fisher’s test (binary variables) or a Chi-square test (for more than two categories).

All variables included in the Table 1 were evaluated in the analyses. In this table, only statistical significant results are shown.

# Baseline measurements expressed in millimeters as a continuous variable.

¶Measurements at one month and one year of follow up, as a dichotomic variable regarding presence or absence.