Skip to main content
. 2018 Jan 17;92(3):e01790-17. doi: 10.1128/JVI.01790-17

TABLE 3.

Parameters for detection of HCV RNA positive and negative strands in CD4+ and CD8+ T cells exposed to authentic, patient-derived HCV

Parameter Value for HCV RNA
Positive strand
Negative strand
7 dpi 10 dpi 14 dpi 7 dpi 10 dpi 14 dpi
CD4 cells
    No. of HCV RNA positive-strand- or negative strand-positive expts/total no. of expts completed 4/4 6/6 5/6 1/4 4/6 3/5
    Overall no. (%) of HCV RNA positive-strand- or negative-strand-positive expts/total no. of expts completed 15/16 (93.7) 8/15 (53.3)
    Mean no. of HCV RNA copies/μg ± SEM 2.7 × 103 ± 1.1 × 103 6.7 × 102 ± 3.8 × 102
CD8 cells
    No. of HCV RNA positive-strand- or negative-strand-positive expts/total no. of expts completed 2/2 6/6 5/6 1/2 3/6 2/5
    Overall no. (%) of HCV RNA positive-strand- or negative-strand-positive expts/total no. of expts completed 13/14 (92.8) 6/13 (46.1)
    Mean no. of HCV RNA copies/μg ± SEM 4.4 × 103 ± 1.3 × 103 1.2 × 102 ± 0.8 × 102