TABLE 1.
Population characteristicsa
| Parameter | All participants (n = 18) | Maraviroc intensification (n = 9) | Standard ART regimen (n = 9) | P valuec |
|---|---|---|---|---|
| Age (yr) | 30 (24, 40.3) | 26 (23, 42.5) | 32 (26, 40.5) | 0.62 |
| Median time from EDIb to ART start, in days (IQR) | 35 (28, 85) | 81 (28, 91) | 33 (26, 85) | 0.37 |
| Time from ART to viral suppression, in days (IQR) | 84 (33–113) | 84 (21–139) | 77 (44–112) | 0.98 |
| Median CD4 count at baseline, cells/mm3 (IQR) | 622.5 (446.8, 760) | 656 (481, 849) | 557 (443.5, 644.5) | 0.43 |
| Median HIV RNA levels at baseline, log10 copies/ml (IQR) | 4.7 (3.7, 5.5) | 4.4 (3.3, 6.7) | 4.9 (4, 5.4) | 0.93 |
| Median duration of follow up, in days (IQR) | 749 (681, 807) | 736 (673, 817) | 761 (676, 834) | 0.86 |
| Median HIV DNA levels at baseline, in copies/1E6 cells (IQR) | 536 (157–902) | 240 (147–773) | 633 (148–912) | 0.60 |
| Median no. of haplotypes (IQR) | 129 (102–150) | 129 (98–140) | 136 (103–179) | 0.43 |
| env | 56 (36–74) | 51 (36–69) | 72 (41–78) | 0.29 |
| gag | 29 (25–35) | 26 (22–39) | 29 (26–34) | 0.68 |
| pol | 40 (31–54) | 46 (30–51) | 37 (31–59) | 0.84 |
a
Median with IQR values are shown for the entire cohort and by groups defined by maraviroc intensification (MVC+ versus MVC−).
b
EDI, estimated date of infection.
c
P values were determined by a two-tailed Mann-Whitney or Fisher exact test.