TABLE 3.
Biomarkers indicative of lethal disease in RVFV-infected AGM
Biomarker | Time point (dpi) |
---|---|
Increased active caspase-3 expression in CD8+ T cells | 2 |
Lack of class II induction on CD8+ T cells | 2 |
Delayed serum IFN-α production | 2 |
Lack of increase in absolute no. of total CD4+ and CD8+ cells | 4 |
Peak febrile response | 7–9 |
Increased no. of WBC | 10 |
Increased no. of granulocytes | 10 |