TABLE 1.
RSV interventions in developmenta
| Name | Classification | Target | Stage |
|---|---|---|---|
| RSV F Vaccine (Novavax) | Vaccine (nanoparticle) | F protein | Phase 3 |
| MEDI-534 | Vaccine (PIV3 vector) | F protein | Phase 2 |
| GSK3389245A | Vaccine (adenovirus vector) | F protein | Phase 2 |
| MEDI-7510 | Vaccine | F protein (postfusion) | Phase 2 |
| DPX-RSV | Vaccine | SH protein (epitope) | Phase 1 |
| CX3C-LbL-NP | Vaccine (nanoparticle) | G protein (epitope) | Preclinical |
| REGN-2222 | MAb | F protein | Phase 3 |
| MEDI-8897 | MAb | F protein | Phase 2 |
| ALX-0171 | Nanobody | F protein | Phase 2 |
| TRL3D3 | MAb | G protein | Pre-INDb |
| GS-5806 | Small molecule | F protein | Phase 2 |
| JNJ-53,718,678 | Small molecule | F protein | Phase 2 |
| BTA-C585 | Small molecule | F protein | Phase 2 |
| AK-0529 | Small molecule | F protein | Phase 2 |
| AK-0529 | Small molecule | F protein | Phase 2 |
| VP-14637 | Small molecule | F protein | Phase 1 |
| RFI-641 | Small molecule | F protein | Preclinical |
| TMC-353121 | Small molecule | F protein | Preclinical |
| BMS-433771 | Small molecule | F protein | Preclinical |
| RSV604 | Small molecule | N protein | Phase 2 |
| ALN-RSV01 | RNAi | N protein | Phase 2 |
| ALS-8176 | Small molecule | L protein | Phase 2 |