2.

Baseline characteristics of patients enrolled in the study (N=110)

Variables	n	%
FIGO, International Federation of Gynecology and Obstetrics; PUD, previous uterine disease; *, Some of the patients presented more than one of the reported symptoms; **, Almost always postoperative staging, except for IVB patients; ***, Evaluated on the surgical specimen report, or on the biopsy.
Age (year) [median (range)]	54	19–77
Symptoms at diagnosis*
No symptoms	23	21
Metrorrhagia	65	59
Abdominal pain	32	29
Dysuria	9	8
Constipation	3	3
Hematuria and rectal bleeding	1	1
FIGO stage**
Stage I	80	73
Stage II	10	9
Stage III	9	8
Stage IVA	7	6
Stage IVB	4	4
Pathological nodal status
pN0	82	75
pN+	3	3
pNx	25	23
Grading***
Grade 1	16	15
Grade 2	9	8
Grade 3	24	22
Not available	61	55
Localization in the uterus
Corpus	89	81
Isthmus cervix	8	7
Fundus	9	8
Not available	4	4
Gynecological history
PUD
Yes	14	13
No	96	87
Pregnancy
Yes	73	66
No	37	34
Previous hormonal therapy
Yes	11	10
No	87	79
Not available	12	11