4.

Statistical results of univariate analysis

Factors	n	5-year OS (%)	95% CI (%)	P	5-year DFS (%)	95% CI (%)	P	5-year LRC (%)	95% CI (%)	P
OS, overall survival; 95% CI, 95% confidence interval; DFS, disease-free survival; LRC, locoregional control; PUD, previous uterine disease; FIGO, International Federation of Gynecology and Obstetrics; TAH, total abdominal hysterectomy; BSO, bilateral salpingo-oophorectomy; RT, radiotherapy; *, last follow-up 55 months.
Median age (year)
<54	55	65	51–79	0.001	50	36–64	0.001	79	67–91	0.051
≥54	55	29	38–64		15	3–27		63	47–79
Grade
1	16	75	50–100	0.040	56	28–84	0.040	71	46–96	0.800
>1 or unknown	94	46	34–58		30	19–41		72	61–83
PUD
Yes	14	73	46–100	0.030	65	37–93	0.008	86	68–100	0.210
No	96	46	34–58		29	19–39		67	56–78
FIGO stage
I	80	59	46–72	<0.001	40	28–52	<0.001	77	66–88	0.002
II, III, or IV	30	21	1–41		16	0–33		58	39–77
FIGO stage
I	80	59	46–72	<0.001	40	28–52	<0.001	77	66–88	0.001
II	10	25	0–59		38	7–69		70	42–98
III	9	0			0			23*	0–60
IV	11	38	1–38		18	0–41		68	37–99
Tumor size (cm)
≤8	41	76	60–92	0.004	54	37–71	0.020	80	66–94	0.490
>8	32	42	20–64		19	3–35		67	48–86
Unknown	37	30	12–48		25	9–41		66	48–84
Tumor size (cm)
≤8	41	76	60–92	0.003	54	37–71	0.006	80	66–94	0.240
>8 or unknown	69	35	21–49		22	11–33		67	54–80
Vascular invasion
Yes	27	36	14–58	0.190	16	0–32	0.040	76	57–95	0.760
No	83	54	41–67		40	28–52		71	60–82
Tumor necrosis
Yes	46	49	32–66	0.310	26	11–41	0.010	74	60–88	0.630
No	64	51	36–66		40	26–54		71	58–84
Type of surgery
TAH±BSO	93	49	37–61	0.540	34	23–45	0.880	70	59–81	0.500
Wertheim	17	54	23–85		34	9–59		79	57–100
Postoperative RT
Yes	75	46	32–60	0.390	33	21–45	0.810	73	61–85	0.400
No	35	59	39–79		36	19–53		67	50–84
Adjuvant chemotherapy
Yes	17	54	22–86	0.870	25	3–47	0.110	66	41–91	0.340
No	93	49	37–61		36	25–47		73	62–84