3.

Univariate and multivariate analysis for factors predictive of DFS (N=1,335)

Prognostic factors	Univariate				Multivariate
	HR	95% CI	P		HR	95% CI	P
DFS, disease-free survival; BMI, body mass index; FIGO, International Federation of Gynecology and Obstetrics; SCC, squamous cell carcinoma; AC, adenocarcinoma; ASC, adenosquamous carcinoma; LNM, lymph node metastasis; LVSI, lymphovascular space invasion; HR, hazard ratio; 95% CI, 95% confidence interval.
Age at diagnosis (year) (≥45 vs. <45)	0.877	0.604–1.273	0.488		–	–	–
BMI (kg/m2) (≥24 vs. <24)	0.941	0.648–1.366	0.749		–	–	–
FIGO stage (Ib vs. IIa)	0.779	0.465–1.306	0.342		–	–	–
Tumor size (cm) (≤4 vs.>4)	0.778	0.534–1.134	0.190		–	–	–
Histology (SCC vs.AC vs. ASC)	0.598	0.278–1.258	0.182		–	–	–
Differentiation (G1–G2 vs. G3)	0.760	0.523–1.105	0.149		–	–	–
LNM (+ vs. –)	3.884	2.664–5.661	0.000		2.911	1.944–4.357	0.000
Stromal invasion (≥1/2 vs. <1/2)	2.117	1.455–3.080	0.000		1.578	1.070–2.326	0.021
LVSI (+ vs. –)	2.804	1.919–4.098	0.000		1.974	1.323–2.946	0.001