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5.

Univariate and multivariate analysis of prognostic factors associated with DFS for cervical SCC (n=1,199)

Prognostic factors Univariate Multivariate
HR 95% CI P HR 95% CI P
DFS, disease-free survival; SCC, squamous cell carcinoma; BMI, body mass index; FIGO, International Federation of Gynecology and Obstetrics; LNM, lymph node metastasis; LVSI, lymphovascular space invasion; HR, hazard ratio; 95% CI, 95% confidence interval.
Age at diagnosis (year) (≥45 vs. <45) 0.812 0.540–1.222 0.317
BMI (kg/m2) (≥24 vs. <24) 0.949 0.631–1.426 0.800
FIGO stage (Ib vs. IIa) 0.816 0.469–1.418 0.469
Tumor size (cm) (≤4 vs.>4) 0.810 0.536–1.223 0.315
Differentiation (G1–G2 vs. G3) 0.881 0.584–1.328 0.544
LNM (+ vs. –) 4.074 2.701–6.144 0.000 3.014 1.942–4.678 0.000
Stromal invasion (≥1/2 vs. <1/2) 2.443 1.625–3.674 0.000 1.831 1.201–2.792 0.005
LVSI (+ vs. –) 2.695 1.779–4.083 0.000 1.828 1.100–2.835 0.007