6.

Univariate and multivariate analysis of prognostic factors associated with OS for cervical SCC (n=1,199)

Prognostic factors	Univariate				Multivariate
	HR	95% CI	P		HR	95% CI	P
OS, overall survival; SCC, squamous cell carcinoma; BMI, body mass index; FIGO, International Federation of Gynecology and Obstetrics; LNM, lymph node metastasis; LVSI, lymphovascular space invasion; HR, hazard ratio; 95% CI, 95% confidence interval.
Age at diagnosis (year) (≥45 vs. <45)	0.982	0.511–1.887	0.956		–	–	–
BMI (kg/m2) (≥24 vs. <24)	1.017	0.527–1.962	0.961		–	–	–
FIGO stage (Ib vs. IIa)	1.002	0.439–2.289	0.996		–	–	–
Tumor size (cm) (≤4 vs.>4)	1.075	0.544–2.124	0.835		–	–	–
Differentiation (G1–G2 vs. G3)	0.397	0.201–0.784	0.006		0.584	0.291–1.173	0.134
LNM (+ vs. –)	8.365	4.279–16.354	0.000		5.804	2.869–11.741	0.000
Stromal invasion (≥1/2 vs. <1/2)	2.118	1.097–4.091	0.022		1.310	0.666–2.576	0.465
LVSI (+ vs. –)	5.692	2.911–11.046	0.000		3.462	1.725–6.950	0.000