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. 2018 Jan 19;4(1):eaao6718. doi: 10.1126/sciadv.aao6718

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Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).

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Fig. 2 — (A) The Aβ-ECFP fusion system used in screening Aβ aggregation inhibitors. (B and C) Screening results of metallohelices A and B from the Aβ-ECFP fusion screen system. (D) Aggregation kinetics of Aβ40 monitored by ThT assay with or without the incubation of A1 and B4. (E) The stopped-flow kinetic study of Aβ and A1. Values show means ± SD, and independent experiments were performed three times.