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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: J Neurochem. 2017 Dec 19;144(3):336–347. doi: 10.1111/jnc.14265

Figure 4.

Figure 4

Effects of Tan-67-mediated activation of DOR on APP expression and processing and BACE-1 level in the ipsilateral penumbral cortex of MCAO mice at 6 and 24 h after MCAO. A, Western blot analysis of APPm, APPim, as well as APP CTF levels at 6 h after MCAO. B, Quantitation of Western blot results shown in (A). C, Western blot analysis of BACE-1 level at 6 h following MCAO. D, Quantitation of BACE-1 level shown in (C). E, Western blot analysis of APPm, APPim, as well as APP CTF levels at 24 h after MCAO. F, Quantitation of Western blot results shown in (E). G, Western blot analysis of BACE-1 level at 24 h following MCAO. H, Quantitation of BACE-1 level shown in (G). Molecular weight markers are indicated as kDa on the right and actin was used as a loading control. All numerical data are shown as mean° SEM; n = 6 mice. * p < 0.05, ** p < 0.01, ***p < 0.001.