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Fibrosis development and progression in a mouse model of steatohepatitis (DIAMOND mouse) and its similarity to human disease. Initially pericellular fibrosis around the central vein is noted followed by both portal and pericellular fibrosis and eventually bridging fibrosis with early nodule formation. Data for mice are shown in the left panels whereas data for humans are shown on the right panel (adapted from asgharpour et al., 7).
