Table 3.

Association between maternal DNMT 3B −149C > T genotype and Down syndrome pregnancy risk among Down syndrome mothers (DSM; n = 111) and control mothers (CM; n = 212).

Model	Overall
	OR	95% CI	P
TT vs. CC	0.47	0.24–0.92	0.03*
CT vs. CC	0.79	0.46–1.38	0.49
TT vs. CT or CC	0.54	0.31–0.96	0.04*
TT or CT vs. CC	0.67	0.40–1.13	0.14
T vs. C	0.69	0.50–0.96	0.03*

^*Significant at p < 0.05.