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. 2018 Jan 1;21(1):90–103. doi: 10.1089/jmf.2017.0016

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© Gian Carlo Tenore et al., 2018; Published by Mary Ann Liebert, Inc.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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FIG. 2. — AMS effects on cell monolayers. Representative microphotographs at a 200 × magnification (20 × objective and a 10 × eyepiece) by phase-contrast light microscopy of human keratinocytes treated for the indicated times (24 and 48 h) with a range of concentrations (from 0.09 to 2.3 mg/mL) of AMS (Annurca apple polyphenolic extract microencapsulated with maltodextrins, AppleMetS). The shown images are representative of three independent experiments. IC₅₀ concentrations of cisplatin (cDDP) are used as positive control for cytotoxicity.