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. 2018 Jan 1;21(1):90–103. doi: 10.1089/jmf.2017.0016

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© Gian Carlo Tenore et al., 2018; Published by Mary Ann Liebert, Inc.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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FIG. 5. — Study flowchart according to the consolidated standards of reporting trials (CONSORT). The diagram shows enrollment and primary efficacy endpoints based on patient diaries, from prescreening to data collection; and the extent of exclusions, loss to follow-up, and completeness of diary documentation available across the entire trial period. AMS, Annurca apple polyphenolic extract microencapsulated with maltodextrins (AppleMetS); AMSbzs, formulation including Annurca apple polyphenolic extract microencapsulated with maltodextrins, biotin, selenium, and zinc (AppleMetS Hair); FAS, full analysis set.