Table 1.
Demographics and clinical information.
| Unmedicated OCD (uOCD) (n = 14) | Medicated OCD (mOCD) (n = 29) | HC (n = 34) | |
|---|---|---|---|
| Age | 26.0 (7.2) | 26.0 (5.5) | 26.7 (7.9) |
| Education (years) | 15.4 (6.9) | 16.0 (2.4) | 16.2 (2.0) |
| Sex | 11 W, 3 M | 14 W, 15 M | 20 W, 14 M |
| Y-BOCS | 24.0 (5.8)a | 19.7 (5.1) | N/A |
| OCD only current | 64.3 (9) | 51.7 (15) | 0 |
| Comorbid anxietyb | 35.7 (5) | 27.6 (8) | 0 |
| Comorbid ICD | 7.1 (1) | 13.8 (4) | 0 |
| Comorbid TD | 0 | 6.9 (2) | 0 |
| Comorbid BDD | 7.1 (1) | 0 | 0 |
| Comorbid MDD | 7.1 (1) | 3.4 (1) | 0 |
| Depression NOS | 0 | 17.2 (5) | 0 |
| Past MDD | 42.9 (6) | 62.1 (18) | 0 |
There were no significant differences between uOCD, mOCD, and HC groups in age, years of education, or sex. Cells in the bottom eight rows represent percentage of patient within the group, with the number of patients in parentheses.
auOCD patients had significantly higher Y-BOCS scores than medicated OCD patients (p = 0.01). For comorbidity counts, patients with multiple disorders contribute to more than one cell; patients with more than one anxiety comorbidity contribute multiple times to the anxiety cell. Chi-square tests revealed no significant differences between uOCD and mOCD patients in proportion of patients displaying the comorbidities listed below (p > 0.20 for all).
bIncludes generalized anxiety disorder (n = 6), social phobia (n = 3), specific phobia (n = 2), and agoraphobia (n = 2).
BDD, body dysmorphic disorder; ICD, impulse control disorder; MDD, major depressive disorder; mOCD, medicated obsessive–compulsive disorder; NOS, not otherwise specified; TD, tic disorder; uOCD, unmedicated obsessive–compulsive disorder; Y-BOCS, Yale-Brown Obsessive–Compulsive Scale.