| Irregular epithelial stratification |
Abnormal variation in nuclear size (anisonucleosis) |
| Loss of polarity of basal cells |
Abnormal variation in nuclear shape (nuclear pleomorphism) |
| Drop-shaped rate ridges |
Abnormal variation in cell size (anisocytosis) |
| Increased number of mitotic figures |
Abnormal variation in cell shape (cellular pleomorphism) |
| Abnormally superficial mitoses |
Increased nuclear-cytoplasmic ratio |
| Premature keratinization in single cells (dyskeratosis) |
Increased nuclear size |
| Keratin pearls within rate pegs |
A typical mitotic figures |
| |
Increased number and size of nucleoli hyperchromasia |
