Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Jan 19;8:1250. doi: 10.1038/s41598-018-19638-x

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

EBOV infection of paradrenal ganglia and peripheral medium myelinated nerves. (a) Low numbers of macrophages infiltrate between ganglion cells in the paradrenal ganglion. Viral intracytoplasmic inclusion bodies (arrows) are present within satellite cells, neurofibroblasts, Schwann cells, and macrophages (H&E). (b) Satellite cells, neurofibroblasts, Schwann cells, and macrophages, and intravascular plasma (EBOV VP40 IHC: DAB chromogen and hematoxylin). (c) Satellite cells, neurofibroblasts, Schwann cells, and macrophages in the ganglion (EBOV NP ISH: fast red chromogen and hematoxylin). (d) Viral intracytoplasmic inclusion bodies (arrows) are present within neurofibroblasts and Schwann cells within a nerve, with low numbers of perivascular infiltrating macrophages (bottom) (H&E). (e) Rare infected Schwann cells and neurofibroblasts within a myelinated nerve (EBOV VP40 IHC: DAB chromogen and hematoxylin). (f) Low numbers of Schwann cells, neurofibroblasts, and infiltrating macrophages within a myelinated nerve (EBOV NP ISH: fast red chromogen and hematoxylin).