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. 2017 May 24;20(1):160–169. doi: 10.1007/s11307-017-1087-5

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© The Author(s) 2017

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 1 — Median values of GTV volume and various imaging parameters including standard deviation at each time-point. a Tumor volume in comparison to ref. [30]. b TBRs. c T2w intensity and ADC. d IE and WO as well as enhancement curves of the T1w imaging with contrast (native, early, and late phases). BL, TP1, TP2, and FU—scan time-points: baseline, 2 and 5 weeks after EBRT start, follow-up (week 19); TBR _max (SUV_max in GTV)/(SUV_mean in gluteal muscle), TBR _peak (SUV_peak in GTV)/(SUV_mean in gluteal muscle); GTV gross tumor volume, SUV _peak standard uptake value measured in a 1-cm³ sphere around SUV_max, ADC apparent diffusion coefficient, T2w T2 weighted MRI, IE initial enhancement defined as (I ^DCE _early − I ^DCE _native)/(I ^DCE _native), WO wash-out rate defined as (I ^DCE _delayed − I ^DCE _early)/(I ^DCE _native).