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. 2017 May 24;20(1):160–169. doi: 10.1007/s11307-017-1087-5

Table 3.

Summary of various patient-related parameters at different time-points and temporal changes with respect to previous time-points and baseline investigations

BL TP1 TP2 FU
Tumor volume (cm3) 68.2 ± 31.1 39.3 ± 18.8 25.7 ± 15.1 13.2a ± 6.0
VolumeTP-TP (%) N/A −43 ± 29 −42p ± 26 N/A
VolumeBL (%) N/A −43 ± 29 −72p ± 23 N/A
TBRmax 3.4 ± 0.9 2.4 ± 0.3 2.3 ± 0.5 2.2 ± 0.5
TBRmax TP-TP (%) N/A −34p ± 12 −3 ± 14 −14 ± 15
TBRmax BL (%) N/A −34p ± 12 −33p ± 12 −32p ± 9
TBRpeak 2.6 ± 0.8 1.6 ± 0.2 1.7 ± 0.3 1.6 ± 0.3
TBRpeak TP-TP (%) N/A −29p ± 12 0 ± 14 4 ± 15
TBRpeak BL (%) N/A −29p ± 12 −34p ± 8 −321p ± 13
T2w 573.0 ± 101.5 543.0 ± 72.4 477.5 ± 96.3 398.5 ± 80.9
T2wTP-TP (%) N/A −6 ± 6 −8 ± 9 −14 ± 12
T2wBL (%) N/A −6 ± 6 −13 ± 8 −27p ± 15
ADC (×10−3 mm2/s) 0.99 ± 0.10 1.21 ± 0.12 1.33 ± 0.14 1.38 ± 0.22
ADCTP-TP (%) N/A 22p ± 8 7 ± 10 3 ± 7
ADCBL (%) N/A 22p ± 8 35p ± 20 41p ± 24
IEb 1.4 ± 0.2 1.9 ± 0.3 2.0 ± 0.4 1.2 ± 0.4
IETP-TP (%)c N/A N/Ap N/A N/Ap
IEBL (%)c N/A N/Ap N/A N/Ap
WOb −0.2 ± 0.1 −0.2 ± 0.2 −0.3 ± 0.1 0.4 ± 0.2
WOTP-TP (%)c N/A N/A N/A N/Ap
WOBL (%)c N/A N/A N/A N/Ap

TBR max (SUVmax in GTV)/(SUVmean in gluteal muscle), TBR peak (SUVpeak in GTV)/(SUVmean in gluteal muscle), SUV peak SUV measured in a 1-cm3 sphere around SUVmax, X TP-TP (value in TPn − value in TPn-1)/(value in TPn-1), X BL (value in TPn − value in BL)/(value in BL)

aVolume of cervix at FU

bIE/WO calculated based on mean values of T1w native/early/late

cNot possible to calculate difference in ratios due to very low denominator value, only significance of change was assessed

pStat. significant (p < 0.05)