Table 2.
Baseline and end point scores in psychometric assessment scales for 27 patients with bipolar depression assigned to a 6-week adjunctive treatment with creatine monohydrate or placebo according to last observation carried forward
| Score | Creatine | Placebo | t | p a | ||
|---|---|---|---|---|---|---|
| Baseline (N = 16) Mean (SD) |
End point (N = 16) Mean (SD) |
Baseline (N = 11) Mean (SD) |
End point (N = 11) Mean (SD) |
|||
| MADRS | 27.1 (5.40) | 13.1 (8.49) | 30.1 (5.19) | 18.3 (9.87) | − 0.591 | 0.560 |
| HAM-D | 15.1 (4.27) | 7.87 (4.96) | 17.8 (3.55) | 12.3 (4.69) | − 0.964 | 0.345 |
| YMRS | 1.31 (1.40) | 4.00 (6.29) | 2.55 (1.64) | 1.82 (2.75) | 1.588 | 0.125 |
| CGI-S | 4.38 (0.50) | 2.94 (0.93) | 4.27 (0.47) | 3.27 (1.19) | − 1.021 | 0.317 |
| FAST | 34.0 (14.7) | 19.2 (16.2) | 50.2 (14.3) | 29.7 (18.9) | 0.512 | 0.615 |
aCalculated by Student’s t test