Figure 4.
Prognostic value of ADAR1 expression in HCC after tumor resection. (a) Representative images for scoring the ADAR1 IHC staining in HCC tumor tissues (left panel) and normal liver tissues (right panel). (b and c) Kaplan–Meier plots for total survival time of patients demonstrating ADAR1-negative (blue line in b; n=25), ADAR1-positive (green line in b; n=58), ADAR1 normal expression or downregulation (blue line in c; n=32) and ADAR1 overexpression (OE) (green line in c; n=51) in tumor tissues (log-rank test). (d and e) Kaplan–Meier plots for disease-free survival time of patients demonstrating ADAR1-negative (blue line in d; n=25), ADAR1-positive (green line in d; n=58), ADAR1 normal expression or downregulation (blue line in e; 32) and ADAR1 overexpression (OE) (green line in e; n=51) in tumor tissue (log-rank test). T, tumor; N, nontumor