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. 2018 Jan 19;8:1278. doi: 10.1038/s41598-018-19754-8

Table 5.

Gene ontology annotation results for genes in modules with a strong correlation (p < 0.05) with treatment or genetic line.

Module Gene No. Biological Process Accession No. P-value Represented Genes
Lightcyan 61 Negative regulation of viral genome replication GO:0045071 0.009 EIF2AK2, OASL, RSAD2, STAT1
Response to virus GO:0009615 0.006 CCL19, EIF2AK2, Mx, OASL, RSAD2
Brown 1383 Translation GO:0006412 2.4E-16 EIF3(I/J), EIF4E(3/BP1), RPL(3/4/6/8/9/12/13/19/21/23/27/31/32/37/39), MRPL(10/20/22/44/47/51), RPS(2/3/7/14/16/21/24/28/29)
Mitochondrial transport GO:0006839 0.022 BCL2L1, BNIP3, MPC(1/2), MTX2, SLC25A(4/17/21/43)
Ribosome biogenesis GO:0042254 0.016 RPL(6/10 A/12/23 A), RPS(10/14/16/21/24/28), UTP(11 L/20)
Cellular component organization GO:0016043 0.006 CHCHD(4/10), COX(17/18/19), EIF3(I/J), KCTD(2/3), RPS(3/10/14/28), RPL(12/23), SLC25A(4/33), SNX(3/5)
Yellow 1303 Cell communication GO:0007154 0.006 CD (4/28/151/180), GPR (27/39/144/149/157/162)
Cellular response to stimulus GO:0051716 0.002 CD (4/28/151/180), EIF2AK1, FAS, GPR (27/39/144/149/157/162), PIK3C2G, PLA2R1, TNFRSF(18/21)
Cellular nitrogen compound biosynthetic process GO:0044271 0.025 CHDH, CMPK, CPEB1, GUCY(1B2/2 C), HOXA7, NPPA, PAPSS1, PHOX2B, RX1, SUPT3H, TERT, THRB, UPP1
Green 1259 Organic substance transport GO:0071702 0.037 CD40LG, EIF5A2, SLC2A(6/9), SLC16A(1/7/10), SLC27A(4/6), SLC(15A4/17A5/18A2/22A3/26A5/29A4/35A3)

Note: Genes within the same family are labeled with the member or subunit names in the brackets.