Table 1.

Eosinophilic esophagitis (EoE) histology scoring system definitions.

Feature	Definition
Eosinophilic inflammation	Based on peak eosinophil count
Basal zone hyperplasia	Basal zone occupies more than 15% of total epithelial thickness
Eosinophil abscess	Eosinophil aggregate that disrupts the underlying epithelial architecture
Eosinophil surface layering	Eosinophils align in one or more rows in the upper third of the epithelium
Dilated intercellular spaces	Intercellular bridges are visible in paracellular spaces
Surface epithelial alteration	Surface epithelial cells stain more darkly than normal and eosinophils that may be present among the altered epithelial cells
Dyskeratotic epithelial cells	Epithelial cells with deeply staining cytoplasm and shrunken hyperchromatic nuclei that generally occur singly and may be found anywhere in the epithelium
Lamina propria fibrosis	Coalesced fibrils form fibers of varying diameter