Table 3.
Association of clinicopathological and prognostic parameters of colorectal carcinoma with N stage
| Variable | N stage | P value | |||
|---|---|---|---|---|---|
| N0 | N1 | N2a | N2b | ||
| Age (years) | |||||
| < 50 | 10 | 8 | 9 | 10 | 0.19 |
| > 50 | 22 | 22 | 10 | 9 | |
| Gender | |||||
| Male | 18 | 13 | 10 | 10 | 0.777 |
| Female | 14 | 17 | 9 | 9 | |
| Laterality | |||||
| Right | 6 | 11 | 5 | 8 | 0.26 |
| Left | 26 | 19 | 14 | 11 | |
| Lymphovascular invasion | |||||
| Present | 0 | 8 | 9 | 10 | < 0.001* |
| Absent | 32 | 22 | 10 | 9 | |
| Grade | |||||
| Well differentiated | 3 | 0 | 0 | 0 | < 0.001* |
| Moderately differentiated | 27 | 26 | 16 | 7 | |
| Poorly differentiated | 2 | 4 | 3 | 12 | |
| Tumor type | |||||
| Adenocarcinoma, NOS | 29 | 27 | 16 | 8 | 0.006* |
| Mucinous carcinoma | 2 | 2 | 2 | 7 | |
| Medullary carcinoma | 1 | 0 | 0 | 1 | |
| Signet ring cell carcinoma | 0 | 1 | 1 | 3 | |
| Perinodal spread | |||||
| Present | 0 | 13 | 15 | 19 | < 0.001* |
| Absent | 32 | 17 | 4 | 0 | |
| Mucinous histology (%) | |||||
| Absent | 26 | 20 | 15 | 7 | 0.006* |
| < 10 | 2 | 6 | 2 | 2 | |
| 10–50 | 3 | 0 | 0 | 4 | |
| > 50 | 1 | 4 | 2 | 6 | |
| Signet ring differentiation | |||||
| Present | 1 | 5 | 2 | 8 | 0.003* |
| Absent | 31 | 25 | 17 | 11 | |
| Medullary differentiation | |||||
| Present | 1 | 0 | 0 | 0 | 0.543 |
| Absent | 31 | 30 | 19 | 19 | |
| Necrosis | |||||
| Absent | 1 | 2 | 3 | 0 | 0.097 |
| Focal | 22 | 20 | 10 | 18 | |
| Widespread | 9 | 8 | 6 | 1 | |
| Tumor infiltrating lymphocytes | |||||
| None | 14 | 15 | 13 | 16 | 0.019* |
| Mild-moderate | 7 | 9 | 5 | 3 | |
| Marked | 11 | 6 | 1 | 0 | |
| Peri-tumoral lymphocytes | |||||
| None | 21 | 24 | 12 | 10 | 0.639 |
| Mild-moderate | 6 | 3 | 4 | 5 | |
| Marked | 5 | 3 | 3 | 4 | |
| Pre-existing polyp | |||||
| Present | 7 | 2 | 1 | 0 | 0.047* |
| Absent | 25 | 28 | 18 | 19 | |
Chi square test applied
* P-value is significant