Table 3.
Cytokine levels among patients that had cataract surgery at RHSP, south-western Uganda
| HIV+ | HIV - | P-value at α = 0.05* | P-value at α = 0.00625§ | |||
|---|---|---|---|---|---|---|
| Cytokine | Median (IQR) | Median (IQR) | ||||
| IL-6 | 1396 | [432, 3999] | 727 | [371, 1338] | 0.180 | 0.180 |
| IFN-g | 753 | [154, 1783] | 154 | [154, 1315] | 0.488 | 0.488 |
| GM-CSF | 1850 | [1632, 1948] | 1399 | [1037, 1681] | 0.001* | 0.001§ |
| TNF-a | 79 | [42, 167] | 42 | [6, 122] | 0.152 | 0.152 |
| IL-2 | 78 | [25 , 147] | 50 | [25, 111] | 0.445 | 0.445 |
| IL-4 | 9 | [9, 44] | 21 | [9, 40] | 0.887 | 0.887 |
| IL-8 | 499 | [409, 1648] | 397 | [291, 573] | 0.030* | 0.030 |
| IL-10 | 243 | [209, 369] | 146 | [72, 175] | 0.000* | 0.000§ |
*Significant at α = 0.05
§Significant at α = 0.00625 corrected with Bonferroni correction for multiple comparisons
GM-CSF, IL-8 and IL-10 were found in significantly higher levels in the HIV positive group compared to the HIV negative group
IL-6 Interleukin 6, IFN-g Interferon –gamma, GM-CSF Granulocyte macrophage colony stimulating factor, TNF-a Tumour necrosis factor alpha, IL-2 Interleukin 2, IL-4 Interleukin 4, IL-8 Interleukin 8, IL-10 Interleukin 10, RHSP Rakai Health Service Programme