Table 5.
Cytokine levels in categorized CD4 count levels among HIV infected individuals that had cataract surgery at RHSP, south-western Uganda
| CD4 < 200cells/mm3 | CD4 ≥ 200cells/mm3 | P-value at α = 0.05* | P-value at α = 0.00625§ | |||
|---|---|---|---|---|---|---|
| Median (IQR) | Median (IQR) | |||||
| IL-6 | 1603 | [374, 3677] | 1190 | [625, 12,463] | 0.446 | 0.446 |
| IFN-g | 753 | [154, 1290] | 1469 | [304, 2898] | 0.539 | 0.539 |
| GM-CSF | 1872 | [1753, 1994] | 1632 | [1307, 1872] | 0.107 | 0.107 |
| TNF-a | 79 | [6, 146] | 230 | [95, 530] | 0.022* | 0.022 |
| IL-2 | 66 | [25, 129] | 147 | [46, 271] | 0.343 | 0.343 |
| IL-4 | 10 | [10, 34] | 90 | [9, 110] | 0.032* | 0.032 |
| IL-8 | 448 | [368, 1364] | 836 | [447, 3439] | 0.319 | 0.319 |
| IL-10 | 232 | [209, 278] | 365 | [250, 535] | 0.109 | 0.109 |
*Significant at α = 0.05
§Significant at α = 0.00625 corrected with Bonferroni correction for multiple comparisons
IL-6 Interleukin 6, IFN-g Interferon –gamma, GM-CSF Granulocyte macrophage colony stimulating factor, TNF-a Tumour necrosis factor alpha, IL-2 Interleukin 2, IL-4 Interleukin 4, IL-8 Interleukin 8, IL-10 Interleukin 10, IQR Interquartile range, RHSP Rakai Health Service Programme