Table 1.
Allelic Expression | Total Expression | |||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Weaning Weight | Adult Weight | Fear Memory | Dio3 | Igf2 | Dio3 | Igf2 | Dnmt1 | Ctcf | ||||||||||
Male | Female | Male | Female | Male | Female | Male | Female | Male | Female | Male | Female | Male | Female | Male | Female | Male | Female | |
FAE+T4 | ↔ | ↔ | ↔ | ↑ | ↑ | ↑ | ↑ | NC | ↑ | NC | ↓ | ↓ | ↑ | ↑ | ↑ | ↑ | ↔ | ↔ |
FAE+Metformin | ↑ | ↑ | ↑ | ↑ | ↑ | ↑ | ↔ | NC | ↑ | NC | ↓ | ↓ | ↑ | ↑ | ↑ | ↑ | ↓ | ↓ |
5-Aza+Metformi n | ↑ | ↑ | ↑ | ↑ | ↑ | ↑ | ↔ | ↔ | ↑ | NC | ↓ | ↓ | ↑ | ↑ | ↑ | ↑ | ↓ | ↓ |
↔ Did not differ from FAE
↓ or ↑ Reversed by treatment
NCT No FAE-related changes