Figure 4.

Adoptive cell therapy and MCMVgp100KGP vaccination delays B16F10 tumor growth. Wild-type (WT) mice were challenged with B16F10 i.d. and 5 days later were mock treated, treated with PMEL transfer, treated with PMEL transfer i.v. and 10⁵ PFU WT MCMV i.p., treated with 10⁵ PFU MCMVgp100KGP i.p. alone, or treated with PMEL transfer i.v. and 10⁵ PFU MCMVgp100KGP i.p. (A) Tumor growth curves of individual mice treated as shown. (B) Combined tumor growth curves and (C) survival from experiment shown in (A). Data are accumulated from two independent experiments with n = 9–10 mice/group total. One mouse from the PMEL and MCMVgp100KGP group did not grow a tumor and was excluded. *p < 0.05; ***p < 0.001.