Table 1.

A proposed-diagnostic criterion for POT based on the clinical, histopathological, and immunohistochemical criteria.^1,2,4

S. No	Diagnostic criteria
1	Clinically, the lesions are asymptomatic, located in tooth-bearing areas, and closely associated with erupting teeth favoring their odontogenic origin.
2	Histopathologically, lesions are composed of loose fibrous connective tissue stroma having stellate-shaped fibroblasts with areas of myxoid degeneration resembling dental papilla covered by peripheral columnar epithelium which itself resembles inner enamel epithelium (covering of columnar epithelium is absent in odontogenic myxomas and odontogenic fibromas).
3	Immunohistochemically, epithelium shows positive expressions of cytokeratins (CK), especially CK5, CK14, and CK19, and mesenchymal tumor cells show positive expression of nestin.