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The epidermis of children with Van der Woude syndrome (VWS) is thicker when compared with the epidermis of children with nonsyndromic cleft lip and palate (NSCLP). A, B, D: Hematoxylin and eosin staining of skin from the hips of children with NSCLP (A) or VWS (B, D). C: Thickness of the epidermis (NSCLP, n = 6; VWS, n = 2). ****P < .0001 after unpaired t test. Scale bar = 100 μm.
