TABLE 1.
Characteristics of Included Children With Cleft Lip and Palate
| Patient | Cleft Type† | Lip Pits | Genotype at rs642961 | Genotype at rs2235371 | IRF6 Mutation |
|---|---|---|---|---|---|
| 1* | BCL+A | Yes | GG | GG | R250Q (de Lima et al., 2009) |
| 2 | UCL+A | Yes | nd | GA | R412X (de Lima et al., 2009) |
| 3 | UCLP+A | No | GG | nd | |
| 4 | CLP | No | GG | GG | |
| 5 | BCLP+A | No | GG | GG | |
| 6 | UCLP | No | GG | GA | |
| 7 | BCLP+A | No | GG | GG | |
| 8 | BCLP+A | No | GG | nd | |
| 9 | UCLP+A | No | GG | GG |
*
This child is the same as individual no. 14 in our previous study (Jones et al., 2010).
†
CP= cleft palate only; CLP = cleft lip/palate; CL = cleft lip only; A = alveolus; U = unilateral; B = bilateral; nd = not determined.