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Peptide affinity towards PBMC, assessed by di-8-ANEPPS fluorescence. The dissociation constant, Kd and the asymptotic minimum value of R, Rmin, were obtained by fitting the experimental data to Equation (3). Values are means ± SEM of at least 3 experiments.
| Peptides | Kd (µM) | Rmin, norm |
|---|---|---|
| VG | - | - |
| VG-Chol | 0.32 ± 0.11 | −0.18 ± 0.01 |
| VG-PEG4-Chol | 0.77± 0.38 | −0.21 ± 0.03 |
| VG-PEG24-Chol | 0.36 ± 0.14 | −0.17 ± 0.01 |
