Table 1.
Passive membrane properties of neurons plated on PDL, PDL supplemented with GCM, PDL/laminin, and astroglial cultures of 20%, 50%, and 100% confluence.
Cell capacitance (pF) | Input resistance (GΩ) | RMP (mV) | |
---|---|---|---|
PDL | 24.1 ± 2.8 (14) | 3.3 ± 0.5 (16) | −47.5 ± 2.6 (16) |
GCM | 23.1 ± 3.4 (14) | 3.6 ± 0.5 (14) | −52.3 ± 2.6 (14) |
PDL/laminin | 17.6 ± 1.6 (9) | 2.2 ± 0.3 (12) | −43.7 ± 2.8 (12) |
20% confluence | 33.6 ± 2.9 (16) c1 | 1.5 ± 0.1 (16) a3, b4 | −46.9 ± 1.8 (16) |
50% confluence | 31.6 ± 2.0 (16) | 1.3 ± 0.2 (17) a3, b4 | −47.3 ± 2.3 (17) |
100% confluence | 37.5 ± 3.5 (18) a1, b1, c3 | 1.1 ± 0.1 (18) a4, b4 | −45.0 ± 1.7 (17) |
Data reported as mean ± SEM. Number of included cells indicated in parentheses. a, b and c superscripts represent significance to PDL, GCM and PDL/laminin groups, respectively. 1, 3, and 4 superscripts denote p < 0.05, 0.001, and 0.0001, respectively (one-way ANOVA with post hoc Bonferroni test).