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. Author manuscript; available in PMC: 2019 Jul 5.
Published in final edited form as: Mol Cell Endocrinol. 2017 Jul 21;469:107–111. doi: 10.1016/j.mce.2017.07.018

Figure 1.

Figure 1

Succinate dehydrogenase (complex II) and epigenetic regulation. SDH is the only membrane-bound enzyme of the Krebs cycle, which is also a functional member (complex II) of the electron transport chain (ETC). SDH forms a complex of four different polypeptides (SDHA, SDHB, SDHC and SDHD) with several other prosthetic groups that include FAD, non-heme iron ubiquinone and heme; TET ten–eleven translocation, KDM lysine (K) demethylase, PHD prolyl hydroxylase